Activity of JNJ-Q2 against Staphylococcus aureus isolated from patients with acute bacterial skin and skin-structure infection obtained during a Phase 2 clinical trial.
نویسندگان
چکیده
JNJ-Q2, a fluorinated 4-quinolone, was very active against both methicillin-susceptible Staphylococcus aureus (n = 42; MIC(50/90), 0.008/0.12 μg/mL) and methicillin-resistant S. aureus (n = 69; MIC(50/90), 0.12/0.12 μg/mL) obtained from patients with acute bacterial skin and skin-structure infection (ABSSSI). Overall moxifloxacin and levofloxacin resistance rates were 31.5% and 46.9%, respectively. These favorable results support the continued clinical development of JNJ-Q2 to treat ABSSSI.
منابع مشابه
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ورودعنوان ژورنال:
- Diagnostic microbiology and infectious disease
دوره 74 1 شماره
صفحات -
تاریخ انتشار 2012